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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC27
All Species:
24.24
Human Site:
S241
Identified Species:
44.44
UniProt:
P30260
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30260
NP_001107563.1
824
91867
S241
Y
I
D
S
A
V
I
S
P
D
T
V
P
L
G
Chimpanzee
Pan troglodytes
XP_511624
824
91839
S241
Y
I
D
S
A
V
I
S
P
D
T
V
P
L
G
Rhesus Macaque
Macaca mulatta
XP_001115994
824
91959
S241
Y
I
D
S
A
V
I
S
P
D
T
V
P
L
G
Dog
Lupus familis
XP_548047
825
91842
S241
Y
I
D
S
A
V
I
S
P
D
T
V
P
L
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_663411
825
91824
S241
Y
I
D
S
T
V
I
S
P
D
N
V
P
L
G
Rat
Rattus norvegicus
NP_001019964
824
91645
S241
Y
I
D
S
A
V
I
S
P
D
N
V
P
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520967
385
43892
Chicken
Gallus gallus
NP_001006331
833
92606
I241
S
Y
I
D
S
A
V
I
S
P
D
A
V
P
L
Frog
Xenopus laevis
NP_001085568
833
92363
I241
S
Y
I
D
P
G
V
I
S
P
D
S
L
P
L
Zebra Danio
Brachydanio rerio
NP_958857
790
87878
Y240
N
M
D
S
S
V
S
Y
I
D
S
S
V
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648093
900
101266
N240
Q
N
Q
H
H
N
S
N
M
V
T
P
I
N
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786824
824
91473
L239
F
T
V
P
S
A
P
L
S
S
R
Q
S
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38042
758
85418
F208
V
D
L
K
R
V
F
F
D
I
A
G
K
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.3
99.1
N.A.
96.9
97.4
N.A.
43.6
94.5
89.6
76.5
N.A.
39.2
N.A.
N.A.
49.2
Protein Similarity:
100
99.8
97.2
99.2
N.A.
98.6
98.5
N.A.
45.2
96.6
94.5
84.3
N.A.
57.4
N.A.
N.A.
67.2
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
0
0
0
26.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
0
13.3
6.6
53.3
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
39
16
0
0
0
0
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
54
16
0
0
0
0
8
54
16
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
47
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
47
16
0
0
0
47
16
8
8
0
0
8
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% K
% Leu:
0
0
8
0
0
0
0
8
0
0
0
0
8
47
16
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
8
0
8
0
0
16
0
0
8
8
% N
% Pro:
0
0
0
8
8
0
8
0
47
16
0
8
47
16
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
16
0
0
54
24
0
16
47
24
8
8
16
8
0
16
% S
% Thr:
0
8
0
0
8
0
0
0
0
0
39
0
0
0
0
% T
% Val:
8
0
8
0
0
62
16
0
0
8
0
47
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
16
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _